The series takes place at the "Worst College in America", located at the edge of town. The school's poor reputation is celebrated by the school's uncaring faculty and staff, constantly shown drinking while teaching and/or trying to avoid teaching altogether. Steve and Frank Smith are twin professors at the college, teaching different subjects with limited success, while Professor Cakes is the father of undergraduate Mark "Baby" Cakes, who spends his time at college with the school staff. Pony Merks is the teacher's aide for the history department at the school, and the most rational of the staff, but still willing to go along with the staff's insane plots to avoid working.