Clone High is set in a high school that is secretly being run as an elaborate military experiment orchestrated by a government office called the Secret Board of Shadowy Figures. The school is entirely populated by clones of famous historical figures that have been created and raised with the intent of having their various strengths and abilities harnessed by the United States military. The principal of the high school, Cinnamon J. Scudworth, has his own plans for the clones, and secretly tries to undermine the wishes of the Board (Scudworth wants to use the clones to create a clone-themed amusement park, dubbed "Cloney Island", a decidedly less evil intention than that of the Board). He is assisted by his robot butler/vice principal/dehumidifier Mr. Butlertron (a parody of Mr. Belvedere), who is programmed to call everyone "Wesley".