The series centers around Dora, an American girl of Indigenous Mexican heritage, with a love of embarking on quests related to an activity that she wants to partake of or a place that she wants to go to, accompanied by her talking purple backpack and anthropomorphic monkey companion named Boots (named for his beloved pair of red boots). Each episode is based around a series of cyclical events that occur along the way during Dora's travels, along with obstacles that she and Boots are forced to overcome or puzzles that they have to solve (with "assistance" from the viewing audience) relating to riddles, the Spanish language, or counting.