Eek! the Cat is about a purple cat named Eek, living in the fictitious city of McTropolis, whose motto is "it never hurts to help". This attitude generally gets him into trouble, from which much of the humor of the show is derived. Other characters include Eek's human family, with whom he cannot communicate via spoken language; Sharky the Sharkdog (his worst nightmare), and Eek's girlfriend, Annabelle.