Jakers! takes place in two different settings, in two different time periods. In the present time (the frame story), Piggley Winks lives in the United States (or Great Britain, according to different versions) and tells stories of his childhood in a rural area in the south of Ireland to his three grandchildren. In flashbacks, he is seen as a child, playing with his friends and going to school in rural Ireland in the mid-1950s. Most of the main characters are anthropomorphic animals—including Piggley and his family, who are all pigs. However, there are normal, non-anthropomorphic animals in the show as well.