Interfection.Master Shake is trying to convince Meatwad that there is no need for him to brush his teeth. He says that dental plaque is a conspiracy invented by toothpaste companies to get people to buy their products. After Meatwad says that Shake wouldn't know because he doesn't have any teeth (which actually isn't true), Shake claims that he got rid of them because he was straight, and that teeth are for gay people -- "that's why fairies come and get them." They then head into Frylock's room and decide to get to the bottom of this, with Shake searching for "teeth, 'plaque conspiracy', and Metallica" on the Internet. After Meatwad tries to convince Shake to include Justin Timberlake in the search, Shake threatens to stab his mouth shut with skewers and cut him up with an ax, causing Meatwad to cry. After he's calmed down, Meatwad notices a pop-up on the screen, which Shake clicks. This, of course, brings more and more pop-ups onto the screen. Eventually, the problem grows and grows until the room itself is full of real-life pop-up ads, and the computer is destroyed by a pop-up slicing the monitor when it is created. However, the ads keep popping up, and they can't be closed out for whatever reason.