Monster Blue Lock project is led by a mysterious Ego Jinpachi to produce the world's greatest striker. The top five players will be registered to play as forwards in the U-20 Cup that takes place in six months, but if you drop out, they forever lose the chance to play for the Japanese team. What is the egoism Ego is looking for in a striker? Isagi and others make up their minds to survive in Blue Lock, and move on to the first selection that can make or break their future soccer career.